TEST -2 (TABLETS AND AEROSOLS)

1. Other than tablet hardness, which method is used to measure the tablet strength?


(a) Thickness (b) Weight Variation (c) Friability (d) Organoleptic Properties

2. Tablets produces whiskering at the tablet edge if-

(a)Deep concave punch are used (b) Punches are in poor condition

(c) both a and b (d) None

3. A low moisture content in tablet formulation which is acceptable acts as a-

(a) Lubricant (b) Glidant (c) Binder (d) Antiadhasive

4. How many tablets require for content uniformity test?

(a)10 (b) 20 (c) 30 (d) 40

5. The dissolution flask is cylindrical with a hemispherical bottom . It is maintain at……….by the constant temperature both.

(a) 37±0.5°C (b) 37±1.0 °C (c) 37±1.5 °C (d) 37±2 °C

6. Excessive moisture may be responsible for-

(a) Capping (b) Lamination (c) Picking (d)Sticking

7. Mannitol is widely used in chewable tablets because….

(a) non-hygroscopic nature (b) slow solubility

(c) Peasant feeling in mouth (d) both a and b (e) All

8 .Which of following is commonly used for direct compression?

(a) Methyl cellulose (b) HPMC (c) Hydroxyl propyl cellulose (d) All (e) None

9. PVP is a-

(a)Water soluble resin (b) Water insoluble resins (c) Waxes (d) Enteric resins

10. The medication can not be delivered directly to the affected area by aerosol in a suitable from such as……

(a) Spray (b) Stable foam (c) Stream (d) Quick breaking foam (e) None

11.The mechanical strength of the tablet can be described as –

(a) Hardness and bending strength (b) Fracture resistance (c) Friability

(d) Crushing strength (e) All

12.Effervescent granules are prepared by-

(a) Wet method (b) Dry method (c) Fusion method (d) both a and c (e) All

13. Sugar coating consists of following steps-

(a) sealing and subcoting (b) Syruping and smoothing

(c) Finishing and polishing (d) All (e) None

14. Inadequate spreading of the coating solution before drying a bumping effect which is know as-

(a) Mottling (b) Roughness (c) Hazing orange peel effect (d) Cracking

15. Drug absorption is better with-

(a) Insoluble drugs (b) Lipid soluble drugs (c) Powder (d) Ionized drugs

16. Dose dumping is a problem in formulation of-

(a) Compressed tablets (b) Suppositories

(c) Soft gelatine capsules (d) Controlled release drug products

17. In vitro dissolution rate studies on drug products are useful bio-availability evaluation if they are correlated with-

(a) Disintegration rate (b)In vivo studies in at least three species of animals

(c) Chemical stability of the drug (d) In vivo studies in human

18. One of material listed below is most commonly use in film coating of tablets-

(a) Hydroxyl propyl Methyl cellulose (b) Acacia (c) Simple syrup (d) Bees wax

19. Among the propellants used in aerosols one of the following is used for topical pharmaceutical aerosols:-

(a) Trichloro monofluoro methane (b) Dichloro difluoro methane

(c) Propane (d) Dichloro tetra fluoro ethane

20. If a drug has a very small volume of distribution (Vd), it is likely that this drug:-

(a)Has a short biological life(b)Dose not accumulate in various tissues and organs

(c) Not bioavailable (d) Will not be effective